A persistent epithelial defect (PED) of the cornea is challenging in the field of ophthalmology. We present the case of a patient with a PED and its alternative management with umbilical cord serum (UCS). The patient who had the PED in both eyes was treated with UCS for 3 weeks. The epithelial defect healed, and complaints decreased at the end of treatment. UCS is an effective alternative in treating patients with PEDs.
Keywords: Persistent epithelial defect, umbilical cord serum, autologous serum, graft-versus-host disease, dry eye disease