BACKGROUND/AIMS

We aimed to evaluate the mean platelet volume levels in patients with fibromyalgia and to determine whether there is a relationship between mean platelet volume and bone mineral density.

MATERIAL and METHODS

One hundred female patients with the diagnosis of fibromyalgia included in the study. The age, gender, weight, height, body mass index, mean platelet volume, fibromyalgia impact questionnaire score, bone mineral density (g/cm2), and T- score of L1-4, femoral neck, and femur total were recorded.

RESULTS

The mean age of the patients was 48.29±10.53 years. The mean platelet volume level and fibromyalgia impact questionnaire score were 10, 45±1.87 fL and 61.71±17.16, respectively. The mean L1-L4 T-score was -1.52±1.26, mean femoral neck T-score was -0.89±0.99, BMD was 0.86±0.13 for L1-4, 0.89±0.13 for the total femur, and 0.75±0.09 for femoral neck. We found increases in the BMD, total, and femoral neck score when MPV decreased. MPV was found higher in osteoporotic fibromyalgia patients compared to normal BMD. No significant correlation was found between MPV and these parameters.

CONCLUSION

The mean platelet volume is meaningful for osteoporosis in fibromyalgia patients. Higher MPV may be related to the reason that osteoporosis is affected by inflammatory processes in fibromyalgia patients.

Keywords: Fibromyalgia, bone mineral density, mean platelet volume