Case Report

Case Report of Systemic Tularemia in Cyprus

10.5152/cjms.2018.301

  • Murat Uncu
  • Kaya Süer
  • Murat Kocaoğlu
  • Mustafa Asım Şafak
  • Kudret Çağlar

Received Date: 18.11.2017 Accepted Date: 28.12.2017 Cyprus J Med Sci 2017;2(3):81-84

Tularemia is a zoonotic infectious disease in the Northern Hemisphere, which is caused by gram-negative Francisella tularensis bacteria with four subtypes. In this article, a case of a 5-year-old girl with oculoglandular, oropharyngeal, and typhoid tularemia accompanied by lymph nodes in the abdomen has been presented. Amoxicillin–clavulanic acid treatment was first applied to the patient who had high fever, neck lymphadenopathy, and crypts in the tonsils.Intramuscular ceftriaxone therapy was started after the expected response could not be obtained. As a result, as there was no improvement in response to both the treatments in the clinical condition of the patient, and the patient was hospitalized. Physical examination revealed the presence of cervical and submandibular lymphadenopathy and left otitis media. Hepatosplenomegaly and bilateral periorbital edema developed on the day after admission to the hospital. The most frequent diseases in the age group of the patient that may cause the observed findings were tried to be excluded by laboratory and radiological data.Upon learning that the patient had contact with the suspected infected rabbit during treatment, Francisella tularensis antibody was ordered for differential diagnosis of tularemia. The test result was reported as 1:80 titre positive. The patient’s treatment was changed to a combination of ciprofloxacin plus amikacin. A gradual improvement was observed, and a follow-up evaluation two weeks later revealed that the patient had recovered with no complication. This case is the first proven case feature and is worthy of showing the importance of getting detailed anamnesis.

Keywords: Tularemia, francisella tularensis, lymphadenopathy