BACKGROUND/AIMS

In this study, it was aimed to evaluate systemic inflammatory markers as prognostic factors in patients with parotid gland tumors.

MATERIAL and METHODS

Between 2014and2019, retrospective analysis of 181 patients who applied to Otorhinolaryngology Clinic and operated due to parotid gland tumor was performed. Additionally, 63 patients without tumor were included in the study as a control group. According to the post-operative histopathological diagnosis, it was divided into two groups as patients with benign and malignant tumors. The patients’ age, gender, pre-operative blood tests, neutrophil-lymphocyte ratio(NLR), platelet-lymphocyte ratio(PLR), MPV-platelet ratio(MPVPR), MPV-lymphocyte ratio(MPVLR) and Systemic inflammatory index(SII) parameters calculated.

RESULTS

RBC, hemoglobin, hematocrit and lymphocyte levels were statistically significantly lower in patients with malign tumor compared to other groups. In addition, compared to benign tumor group, NLR, PLR and SII levels significantly increased and MPVLR level significantly decreased in patients with malign tumor. Consequently, according to ROC analysis for malign tumor, RDW, lymphocyte, NLR, PLR, MPVLR and SII were significant prognostic factors (P = .036, P = .002, P = .033, P = .004, P = .001, P = .049, respectively).

CONCLUSION

RDW, lymphocyte, NLR, PLR, MPVLR and SII parameters, which are fast, cheap and easy to use, can be used in the differential diagnosis of benign and malignant masses in patients with parotid gland tumors.

Keywords: Parotid gland tumors, red cell distribution width, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, systemic inflammatory index