Cyprus Journal of Medical Sciences
Original Article

Histopathological Profile of Surgically Excised Scalp and Skull Lesions


Department of Pathology, Ahi Evran University School of Medicine, Kırşehir, Turkey


Department of Neurosurgery, Ahi Evran University School of Medicine, Kırşehir, Turkey

Cyprus J Med Sci 2018; 3: 63-67
DOI: 10.5152/cjms.2018.442
Read: 1507 Downloads: 390 Published: 23 July 2019


BACKGROUND/AIMS: Although subcutaneous lesions of the scalp are more common than those of the skull, few studies in literature have assessed the frequency of scalp and skull diseases. The goal of this study was to establish the frequency and main histopathological findings of these lesions. Our study is one of the largest series and shows that the incidence of surgically excised scalp masses includes an array of diseases.

: We reviewed 265 extracranial masses from 173 patients. The mean age of the patients, gender distribution, localization and characteristics of lesions, histopathological type and radiological features were analyzed.


RESULTS: One-hundred (57.8%) patients were males and 73 (42.2%) were females. The mean age was 42.98 (range, 5-87). In total, 261 were within the scalp, 1 involved the scalp and skull and 3 were within the limits of the skull. Six lesions exhibited malignant features. There were 101 trichilemmal cysts; 74 epidermal cysts; 38 intradermal nevus; 8 verruca vulgaris; 5 squamous cell papilloma; 4 seborrheic keratosis; 4 capillary hemangioma; 3 compound nevus; 3 proliferating trichilemmal cyst; 2 blue nevus; 2 neurofibroma; 2 basal cell carcinoma; 2 langerhans cell histiocytosis; 2 fibrolipoma; 2 folliculitis decalvans and 1 case each of lipoma, dermoid cyst, pilomatricoma, cylindroma, nodular hidradenoma, apocrine cystadenoma, arteriovenous malformation, fibroepithelial polyp, folliculitis, malignant proliferating trichilemmal tumor, follicular carcinoma metastasis, fibrous dysplasia and inflamed fistula tract. No recurrence was seen except for 1 lesion.


CONCLUSION: Although the involvement of the skull is rare, scalp masses present a wide histopathologic spectrum of that arise in all ages. Overall, a majority of these lesions are benign and the presence of a malignant tumor or metastatic tumor presenting as a skull mass is less common. Lesions having intracranial/extracranial extensions may be treated with complete resection followed by skull reconstruction and a close follow-up is necessary.

Cite this article as
: Kilitci A, Asan Z. Histopathological Profile of Surgically Excised Scalp and Skull Lesions. Cyprus J Med Sci 2018; 3: 63-7.

ISSN 2149-7893 EISSN 2536-507X