Cyprus Journal of Medical Sciences
Original Article

Systemic Inflammatory Markers as a Prognostic Factor in Parotid Gland Tumors

1.

Department of Otorhinolaryngology, Gaziantep University, Gaziantep, Turkey

Cyprus J Med Sci 2021; 6: 171-176
DOI: 10.5152/cjms.2021.2718
Read: 27 Downloads: 19 Published: 15 April 2021

Objectives: In this study, it was aimed to evaluate systemic inflammatory markers as prognostic factors in patients with parotid gland tumors.

Patients and Methods: Between 2014and2019, retrospective analysis of 181 patients who applied to Otorhinolaryngology Clinic and operated due to parotid gland tumor was performed. Additionally, 63 patients without tumor were included in the study as a control group. According to the post-operative histopathological diagnosis, it was divided into two groups as patients with benign and malignant tumors. The patients\' age, gender, pre-operative blood tests, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), MPV-platelet ratio (MPVPR), MPV-lymphocyte ratio (MPVLR) and Systemic inflammatory index (SII) parameters calculated.

Results: RBC, hemoglobin, hematocrit and lymphocyte levels were statistically significantly lower in patients with malign tumor compared to other groups. In addition, compared to benign tumor group, NLR, PLR and SII levels significantly increased and MPVLR level significantly decreased in patients with malign tumor. Consequently, according to ROC analysis for malign tumor, RDW, lymphocyte, NLR, PLR, MPVLR and SII were significant prognostic factors (p=0.036, p=0.002, p=0.033, p=0.004, p=0.001, p=0.049, respectively).

Conclusion: RDW, lymphocyte, NLR, PLR, MPVLR and SII parameters, which are fast, cheap and easy to use, can be used in the differential diagnosis of benign and malignant masses in patients with parotid gland tumors.

Cite this article as: Tunc¸ O,Go¨nu¨ldas B, Kanlıkama M. Systemic Inflammatory Markers as a Prognostic Factor in Parotid Gland Tumors. Cyprus J Med Sci 2021; 6(2): 171-176.

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ISSN 2149-7893 EISSN 2536-507X