Cyprus Journal of Medical Sciences
Original Article

The Effect of Staging Laparoscopy Prior to Neoadjuvant Chemotherapy on Treatment Management in Locally Advanced Gastric Cancer

1.

Department of General Surgery, Dokuz Eylül University School of Medicine, İzmir, Turkey

2.

Department of Radiology, Dokuz Eylül University School of Medicine, İzmir, Turkey

3.

Department of Pathology, Dokuz Eylül University School of Medicine, İzmir, Turkey

Cyprus J Med Sci 2019; 4: 95-98
DOI: 10.5152/cjms.2019.964
Read: 107 Downloads: 64 Published: 29 August 2019

BACKGROUND/AIMS

The prevalence of gastric adenocarcinoma is 951.000 in the world and cases in Western countries are diagnosed in a more advanced stage. In this study, the efficacy of neoadjuvant chemotherapy in gastric cancer was demonstrated and neoadjuvant chemotherapy was recommended for patients with ≥T2 resectable gastric tumors. The key point for administering neoadjuvant chemotherapy is the distant location of a solid organ and the status of peritoneal metastasis at the beginning of the treatment. We aimed to investigate the effect of the peritoneal status, which is assessed using staging laparoscopy, on the treatment protocol of gastric cancer patients.

 

MATERIAL and METHODS

This retrospective study included 60 neoadjuvant chemotherapy patients, who were divided into 2 groups according to staging methods.

 

RESULTS

Out of a total of 60 patients, 30 were staged by radiological methods and staging laparoscopy prior to neoadjuvant chemotherapy. The remaining 30 patients were staged only by radiological methods. In the laparoscopic staged group, peritoneal metastases were detected in 43% of radiologically non-metastatic patients by staging laparoscopy. In the non-laparoscopic staged group, metastatic disease was identified in 7 patients, right before or during the gastrectomy operation.

 

CONCLUSION

Peritoneal metastasis is not uncommon in gastric cancer. If the evaluation of peritoneal status is made only by radiological examinations, the treatment may be started with an incorrect low-grade diagnosis. The use of staging laparoscopy prior to neoadjuvant chemotherapy makes a significant contribution to the multidisciplinary treatment of gastric cancer.

 

Cite this article as: Derici S, Altay C, Ünlü M, Atila K. The Effect of Staging Laparoscopy Prior to Neoadjuvant Chemotherapy on Treatment Management in Locally Advanced Gastric Cancer. Cyprus J Med Sci 2019; 4(2): 95-8.

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ISSN2149-7893 EISSN 2536-507X
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