Advanced Stage Buccal Carcinoma: Effect of Local Extension on Prognosis
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Original Article
P: 52-56
December 2017

Advanced Stage Buccal Carcinoma: Effect of Local Extension on Prognosis

Cyprus J Med Sci 2017;2(3):52-56
1. Department of Otolaryngology, Kırıkkale University School of Medicine, Kırıkkale, Turkey
2. Department of Otolaryngology, Ankaran Oncology Training and Research Hospital, Ankara, Turkey
3. Department of Otolaryngology, Erzincan University School of Medicine, Erzincan, Turkey
No information available.
No information available
Received Date: 16.11.2017
Accepted Date: 27.11.2017
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ABSTRACT

BACKGROUND/AIMS

The aim of this study was to evaluate the effects of alveolar mucosa, bone, cheek skin, and lip invasion of buccal carcinoma on locoregional recurrence and survival rates.

MATERIALS and METHODS

The study included 36 patients with T3-T4a buccal carcinoma. Both T3 and T4a tumors were divided into two subgroups: T3 tumors limited to buccal mucosa, T3 tumors with the involvement of alveolar mucosa, T4a tumors with bone invasion, and T4a tumors with skin and/or lip invasion.

RESULTS

In T3-T4a tumors, the rates of tumors limited to the buccal mucosa, tumors involving alveolar mucosa, bone of either the maxilla or mandible, and skin and/or lips were 25%, 22.2%, 33.3%, and 19.4%, respectively. The 3-year disease-free survival rate of patients with T3 and T4a tumors was 70.6% and 52.6%, respectively. The 5-year disease-free survival rate of patients with T3 and T4a tumors was 58.8% and 42.1%, respectively. Regarding the 3- and 5-year survival rates, no statistically significant difference was observed between T3 and T4a tumors and between their subgroups.

CONCLUSION

Despite the lack of statistical significance, there seemed to be a trend toward worse survival among the patients with bone invasion.